Nona Biosciences is at the forefront of biotechnological advancements, offering a comprehensive range of services that revolutionize the field of antibody discovery and development. With their cutting-edge technologies and expertise, Nona Biosciences empowers partners worldwide, including academic institutions, biotech startups, and major biopharmaceutical companies, to accelerate the development of transformative next-generation drugs. Let’s dive into the remarkable services they provide.
- Antibody Discovery Solution:
Nona Biosciences offers a one-stop solution for therapeutic antibody discovery, engineering, and development. Their integrated approach covers every stage of the process, from antigen design and production to cell line generation, in vitro functional assays, and antibody production. By utilizing their advanced Harbour Mice® platform, which generates fully human monoclonal antibodies, nona service Biosciences ensures the development of highly effective and safe therapeutic antibodies. - Harbour Mice® Platform:
At the core of Nona Biosciences’ success lies their proprietary Harbour Mice® platform. This platform utilizes transgenic mice with fully human immunoglobulin genes, enabling robust B cell development and antibody maturation. The Harbour Mice® platform offers two formats: H2L2, which features fully human monoclonal antibodies in two heavy and two light chains, and HCAb, a unique platform for generating fully human heavy chain-only antibodies. These platforms have received global IP protection and are clinically validated, ensuring reliable and high-quality antibody discovery. - Beacon® Single B Cell Screening:
Nona Biosciences leverages the Beacon® single B cell screening platform to enhance the efficiency and accuracy of antibody discovery. By screening individual B cells, they can identify and isolate rare and potent antibodies with exceptional specificity and binding affinity. This innovative technology significantly expedites the lead generation and engineering process, facilitating the development of novel biotherapeutics. - Antibody Engineering and Characterization:
To optimize the properties and functionalities of therapeutic antibodies, Nona Biosciences provides comprehensive antibody engineering services. These services include affinity maturation, liability engineering, and Fc engineering, which enhance binding affinity, stability, and effector functions of antibodies. Furthermore, Nona Biosciences conducts in vitro and in vivo characterization studies, assessing pharmacokinetics, pharmacodynamics, and efficacy to ensure the development of safe and effective therapeutic candidates. - Flexible Business Models:
Nona Biosciences understands the diverse needs of their partners and offers flexible business models to maximize value. They provide technology licensing opportunities, enabling other organizations to leverage their cutting-edge platforms. Additionally, Nona Biosciences’ Harbour Mice® platforms have been extensively validated and widely used in both industry and academia, establishing them as a trusted and reliable partner.
In conclusion, Nona Biosciences is a leading global biotechnology company offering state-of-the-art services for antibody discovery and development. With their innovative technologies, such as the Harbour Mice® platform and Beacon® single B cell screening, they empower partners to accelerate the creation of groundbreaking biotherapeutics. Through flexible business models and a commitment to excellence, Nona Biosciences is revolutionizing the biotechnology landscape and driving global biotherapeutic innovation.